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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1528 | Angiotensin I/II (1-5) | Angiotensin I/II 1-5 | RAAS , Others |
Angiotensin I/II (1-5) is a peptide (ASP-ARG-VAL-TYR-ILE) that contains the amino acids 1-5 and is converted from Angiotensin I/II. | |||
TP1579 | Angiotensin I/II (1-6) | Angiotensin I/II 1-6 | RAAS , Others |
Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) that contains the amino acids 1-6 and is converted from Angiotensin I/II peptide. | |||
T7577 | Angiotensin III, human, mouse | Angiotensin III, human, mouse(3TFA) | RAAS |
Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA))(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM). | |||
T8560 | Angiotensin II human acetate | Ang II acetate,DRVYIHPF acetate,Angiotensin II acetate | Apoptosis , RAAS |
Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor. | |||
T7339 | Angiotensin (1-7) | Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO | RAAS , Endogenous Metabolite |
Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) is a synthetic heptapeptide identical to endogenous angiotensin-(1-7) , inhibits purified canine ACE activity (IC50=0.65 μM) with vasodilator and antiproliferative activiti... | |||
T7040 | Angiotensin II human | DRVYIHPF,Angiotensin II,Hypertensin II,Ang II | Apoptosis , RAAS |
Angiotensin II human (Ang II) is a biologically active peptide, a vasoconstrictor. Angiotensin II interacts with AT1R and AT2R to regulate blood pressure, stimulate sympathetic nerves, and increase aldosterone biosynthes... | |||
TP1929L1 | Saralasin acetate(34273-10-4 free base) | RAAS | |
Saralasin acetate is a Non-selective angiotensin II antagonist. | |||
T3178 | BIBS 39 | RAAS | |
BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist. | |||
T2531 | Eprosartan Mesylate | SKF-108566J | RAAS |
Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker. | |||
T7354 | H-Val-Pro-Pro-OH | RAAS | |
H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM). | |||
T1461 | Candesartan | CV 11974 | RAAS |
Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure. | |||
T22344 | Icatibant Acetate | Bradykinin Receptor | |
Icatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema. | |||
T5S0106 | Peimisine | Ebeiensine | RAAS , AChR |
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe... | |||
T13376 | YS-49 | RAAS , Akt , PI3K , Adrenergic Receptor | |
YS-49 is an activator of PI3K/Akt (a downstream target of RhoA). | |||
T5355 | Sparsentan | RE-021,DARA-a | RAAS , Endothelin Receptor |
Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM, respectively) | |||
T6067 | PD 123319 | (S)-(+)-PD 123319,PD123319 | RAAS |
PD 123319 ((S)-(+)-PD 123319) is a potent, selective AT2 angiotensin II receptor antagonist. | |||
T1570 | Telmisartan | BIBR 277 | RAAS , Autophagy |
Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist. | |||
T0215L | Losartan | DuP-753 | RAAS |
Losartan (DuP-753) is an angiotensin II receptor antagonist. | |||
T7797 | Tasosartan | WAY-ANA 756 | RAAS |
Tasosartan (WAY-ANA 756) is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM). | |||
T6219 | Azilsartan Medoxomil | TAK-491 | RAAS |
Azilsartan Medoxomil (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. |